Breast cancer histologic grading using digital microscopy: concordance and outcome association
نویسندگان
چکیده
منابع مشابه
Grading Breast Cancer Tissues Using Molecular Portraits*
Tumor progression and prognosis in breast cancer patients are difficult to assess using current clinical and laboratory parameters, where a pathological grading is indicative of tumor aggressiveness. This grading is based on assessments of nuclear grade, tubule formation, and mitotic rate. We report here the first protein signatures associated with histological grades of breast cancer, determin...
متن کاملMethod for grading breast cancer.
labelling.' PCNA immunohistochemical expression (evaluated with the PCI0 mono-clonal antibody) seems to be related to cellular proliferation in many normal tissues and in some neoplasms,2 such as gastro-intestinal lymphomas,3 central nervous system tumours,4 lung neuroendocrine neoplasms,' and prostatic carcinomas.' However, in other tumours, like breast and gastric cancer, PCNA (PC 10) express...
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چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولDigital Microscopy Assessment of Angiogenesis in Different Breast Cancer Compartments
BACKGROUND/AIM Tumour angiogenesis defined by microvessel density (MVD) is generally accepted as a prognostic factor in breast cancer. However, due to variability of measurement systems and cutoffs, it is questionable to date whether it contributes to predictive outline. Our study aims to grade vascular heterogeneity by comparing clear-cut compartments: tumour associated stroma (TAS), tumour pa...
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Background: The relationship between thyroid autoimmunity and breast cancer is a challenging subject. We aimed to investigate this association in women with breast cancer. Methods: In this descriptive study, 41 women with newly diagnosed breast cancer before receiving any pharmacologic treatment and 38 healthy age-matched women were enrolled. Anti TPO Ab (anti-thyroid peroxidase antibodies), FT...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 2018
ISSN: 0021-9746,1472-4146
DOI: 10.1136/jclinpath-2017-204979